How does one apply for access authorization?

The procedure to apply for access authorization for CGHub is the same as it is for the NCBI Database of Genotypes and Phenotypes (dbGaP). Before you apply, you must have an eRA Commons account:

  • eRA Commons (for NIH Extramural principal investigators, grantees, or other extramural investigators). If you do not have a pre-existing eRA Commons account, register here.
For additional information, see request procedures for Principal Investigators and Signing Officials.

Who can apply?

Researchers from outside of NIH need to be identified as Principal Investigators (PIs) in the eRA Commons system. If you are not a PI, when you log in, the system will advise you to contact your local supervisor to apply on your behalf.

NIH Intramural employees can apply if they are registered in the NIH Intramural Database (NIDB) as a PI, PI-eligible, or Lead Investigator. NIH Administrative and Extramural staff can apply if they meet specified criteria. When NIH employees log in, the system will recognize their status and direct them to obtain any necessary approvals and fill out any required forms. For further information, see NIH Feb. 6, 2008 memo on Requesting Access to Data in the NIH GWAS Data Repository.

The Code of Conduct is an agreement that research investigators agree to abide by as Approved Users of data received through dbGaP and CGHub. Failure to abide by any term within this Code of Conduct may result in the revocation of approved access to any or all datasets obtained through CGHub.

Why is access restricted?

NIH is committed to respecting the privacy and intentions of research participants with regard to how data pertaining to their individual information is used. Access to DNA and related types of sequence information via CGHub is therefore intended only for scientific investigators pursuing research questions that are consistent with the informed consent agreements provided by individual research participants. Clinical and other non-sequence-related data for the TCGA cases represented at CGHub has different access restrictions, and is accessed through the TCGA Data Coordinating Center. For both types of data, investigators provided access will be expected to utilize appropriate data security measures.

Who is an authorized user within the data access request system?

Authorized users include the researchers who may request data sets for specific research uses, the Institutional Signing Officials from the PI's home organization who certify and submit such requests, and the NIH staff who review and process requests (e.g., members of the Data Access Committees).

Do you need further help?

CGHub also maintains a help desk to assist investigators, institutional signing officials and NIH staff with authorized access management, and answer any questions related to the application process. Contact CGHub Technical Support with your queries.


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